Frontline Plus vs Nexgard: Which Flea & Tick Treatment?

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Is your furry friend constantly scratching? Fleas and ticks are more than just a nuisance; they can transmit diseases and cause serious health problems. Choosing the right preventative treatment is crucial for your pet’s well-being. This comparison dives deep into two popular choices: Frontline Plus and NexGard.

Both Frontline Plus and NexGard offer protection against fleas and ticks, but they work in different ways and have varying characteristics. Understanding the differences between these two treatments can help you make an informed decision and ensure your pet stays happy and healthy. We’ll explore their effectiveness, application methods, and potential side effects.

Whether you’re a seasoned pet owner or new to the world of flea and tick prevention, this guide will provide the insights you need. We’ll examine the key features of Frontline Plus and NexGard, helping you determine which product best suits your pet’s needs and lifestyle. Get ready to discover the best defense against these pesky parasites!

Specs at a Glance:

Feature Frontline Plus Nexgard
Active Ingredients Fipronil, (S)-Methoprene Afoxolaner
Target Pests Fleas, Ticks, Chewing Lice Fleas, Ticks
Application Method Topical Oral Chewable
Frequency of Application Monthly Monthly
Flea Kill Speed Kills fleas within 18 hours Kills fleas within 8 hours
Tick Kill Speed Kills ticks within 48 hours Kills ticks within 24-48 hours
Waterproof Yes Yes
Age/Weight Restrictions Varies by product size; typically for puppies 8 weeks or older Varies by product size; typically for puppies 8 weeks or older
Available Forms Topical applicators Chewable tablets
Prevents Flea Eggs Yes No
Prescription Required No Yes
Manufacturer Boehringer Ingelheim Boehringer Ingelheim

Feature-by-Feature Breakdown

Active Ingredients

  • Frontline Plus: Contains fipronil and (S)-methoprene. Fipronil kills adult fleas and ticks, while (S)-methoprene prevents flea eggs and larvae from developing. It’s a topical application.
  • Nexgard: Contains afoxolaner. Afoxolaner is an isoxazoline that kills fleas and ticks by overstimulating their nervous systems. It’s an oral chewable.
  • Winner: Nexgard

Administration Method

  • Frontline Plus: Applied topically, usually to the skin between the shoulder blades. This can be easier for some pet owners, especially those who struggle to get their pet to take oral medication. However, it requires careful application and can be messy.
  • Nexgard: Administered as a chewable tablet, which is typically readily accepted by dogs due to its beef flavor. This can be easier for pet owners who find topical applications difficult.
  • Winner: Nexgard

Flea Control

  • Frontline Plus: Kills adult fleas and prevents flea eggs and larvae from developing, providing comprehensive flea control. It offers good flea control but may take longer to kill existing fleas.
  • Nexgard: Rapidly kills fleas, often within hours of administration. Provides fast-acting flea control.
  • Winner: Nexgard

Tick Control

  • Frontline Plus: Kills ticks, including deer ticks, American dog ticks, lone star ticks, and brown dog ticks. Effective against ticks, but efficacy may vary depending on tick species and exposure.
  • Nexgard: Kills ticks, including black-legged ticks, American dog ticks, lone star ticks, and brown dog ticks. Provides effective and consistent tick control.
  • Winner: Nexgard

Longevity of Protection

  • Frontline Plus: Provides protection against fleas and ticks for up to 30 days. Requires monthly application.
  • Nexgard: Provides protection against fleas and ticks for 30 days. Requires monthly administration.
  • Winner: Tie

Water Resistance

  • Frontline Plus: Generally considered waterproof after 24 hours of application. Bathing or swimming within 24 hours of application is not recommended.
  • Nexgard: Not affected by water, so dogs can swim and bathe without impacting its effectiveness.
  • Winner: Nexgard

Cost

  • Frontline Plus: Typically more affordable than NexGard. May be a budget-friendly option for some pet owners.
  • Nexgard: Generally more expensive than Frontline Plus.
  • Winner: Frontline Plus

Side Effects

  • Frontline Plus: Side effects are rare but can include skin irritation at the application site.
  • Nexgard: Side effects are uncommon but can include vomiting, lethargy, diarrhea, and decreased appetite.
  • Winner: Frontline Plus

Winner by Category:

Category Winner
Ease of Administration Tie
Flea Egg Prevention Frontline Plus
Speed of Flea Kill Nexgard
Speed of Tick Kill Nexgard
Availability Frontline Plus

What They Have in Common:

  • Monthly Application: Both Frontline Plus and Nexgard require monthly applications to maintain protection against fleas and ticks. This consistent schedule is crucial for continuous pest control.
  • Broad Spectrum Protection: Both products are designed to kill fleas and ticks, providing a broad spectrum of protection against these common parasites.
  • Easy to Administer: Both products are relatively easy to administer, with Frontline Plus being a topical solution and Nexgard being a chewable tablet.
  • Effective in Killing Pests: Both medications are effective in killing existing fleas and ticks on your dog.
  • Manufactured by Reputable Companies: Both Frontline Plus and Nexgard are produced by well-known and reputable pharmaceutical companies.

Frontline Plus Vs Nexgard Buying Guide

Effectiveness Against Fleas and Ticks

Frontline Plus and Nexgard both offer excellent protection against fleas and ticks, but they achieve this through different means. Frontline Plus utilizes fipronil and (S)-methoprene, which work by disrupting the nervous systems of these parasites. Nexgard uses afoxolaner, an isoxazoline that similarly targets the nervous system of fleas and ticks. Both products are highly effective at killing existing infestations and preventing new ones. The choice often comes down to individual preference and any potential sensitivities a pet might have.

Application and Administration

Frontline Plus is a topical treatment, applied directly to the skin, typically between the shoulder blades. This method is convenient for many pet owners. Nexgard, on the other hand, is an oral chewable tablet, which some owners find easier to administer, especially with pets that dislike topical applications. The ease of application can significantly impact compliance with the treatment schedule, a crucial factor in ensuring continuous protection. Consider your pet’s temperament when deciding between these two.

Safety and Side Effects

Both Frontline Plus and Nexgard are generally considered safe for use in dogs. However, as with any medication, there is a potential for side effects. Frontline Plus may occasionally cause mild skin irritation at the application site. Nexgard, while generally well-tolerated, has been associated with rare instances of vomiting, diarrhea, lethargy, and in very rare cases, neurological effects. Always consult with your veterinarian if you notice any adverse reactions after treatment. Careful observation is key.

Cost and Availability

The cost of Frontline Plus and Nexgard can vary depending on the size of your dog and the retailer. Generally, Nexgard tends to be slightly more expensive. Both products are readily available at veterinary clinics, pet stores, and online retailers. Consider the long-term cost, as regular treatment is necessary for ongoing protection. Comparing prices and considering the number of doses per package can help you make a cost-effective decision that fits your budget.

Duration of Protection

Frontline Plus provides protection against fleas and ticks for approximately 30 days. This means you need to reapply the topical treatment monthly. Nexgard offers a longer duration of protection, with a single chewable tablet providing protection for a full month. This longer duration can be a significant advantage for pet owners who prefer a less frequent dosing schedule. Compliance with the recommended dosage schedule is essential for the products’ efficacy.

Pet’s Health and Breed Considerations

While both products are safe for most dogs, it’s important to consider your pet’s individual health and breed. Consult with your veterinarian, especially if your dog has any pre-existing health conditions or if you have specific breed-related concerns. Some breeds might be more sensitive to certain medications. Your vet can provide tailored advice based on your dog’s individual needs and recommend the most suitable product for optimal flea and tick control. Always prioritize your pet’s health.

Who Should Buy What?

Buy Frontline Plus If…

  • You prefer a topical application method.
  • You want a product that also prevents flea eggs from hatching.
  • You prefer an over-the-counter option.
  • Your dog is sensitive to oral medications.

Buy Nexgard If…

  • You prefer an oral chewable medication.
  • You want a faster-acting flea and tick killer.
  • You have a dog that readily accepts chewable treats.
  • You don’t mind getting a prescription from your vet.

Frequently Asked Questions

How does Frontline Plus work?

Frontline Plus contains fipronil, which disrupts the nervous systems of fleas and ticks, killing them. It also contains (S)-methoprene, an insect growth regulator that prevents flea eggs and larvae from developing into adults. This dual action provides comprehensive protection, breaking the flea life cycle and preventing infestations. The active ingredients are stored in the oil glands of the skin.

How does Nexgard work?

Nexgard contains afoxolaner, an isoxazoline that works by interfering with the nerve transmission of fleas and ticks, leading to their paralysis and death. It is absorbed into the bloodstream after ingestion and is distributed throughout the body. Nexgard effectively kills fleas and ticks within hours, providing rapid relief and prevention.

Is Frontline Plus safe for puppies?

Frontline Plus is generally considered safe for puppies, typically for those 8 weeks of age or older and weighing at least 2 pounds. However, it’s always best to consult with your veterinarian before starting any flea and tick treatment for your puppy. They can assess your puppy’s individual health and recommend the most appropriate product.

Is Nexgard safe for pregnant or nursing dogs?

The safety of Nexgard for pregnant or nursing dogs has not been fully established. Therefore, it is generally recommended to consult with your veterinarian before using Nexgard on pregnant or nursing dogs. They can assess the risks and benefits and provide guidance based on your dog’s individual circumstances and health.

How often should I apply Frontline Plus?

Frontline Plus should be applied monthly to provide continuous protection against fleas and ticks. It’s crucial to follow the recommended application schedule to maintain effectiveness and prevent re-infestation. Set a reminder or mark your calendar to ensure you don’t miss a dose. Consistent application is key for optimal results.

How often should I give Nexgard?

Nexgard is administered orally once a month. The medication is given as a chewable tablet. Ensure your dog consumes the entire tablet. It is important to give the dose on the same day each month to maintain consistent protection. This consistent schedule is vital for maintaining year-round protection against fleas and ticks.

What if I miss a dose of Frontline Plus or Nexgard?

If you miss a dose of Frontline Plus, reapply it as soon as you remember and then continue with your regular monthly schedule. For Nexgard, give the dose as soon as you remember. If it is close to the next scheduled dose, give both doses. Monitor your pet for any signs of fleas or ticks and consult your veterinarian for further advice. Consistency is the key to preventing infestations.

Final Verdict

Both Frontline Plus and Nexgard are effective flea and tick preventatives. Frontline Plus provides reliable protection through a topical application, while Nexgard offers the convenience of an oral chew. While both products are safe, Nexgard’s longer duration of protection and ease of administration may be preferable for some pet owners. Ultimately, the best choice depends on individual needs and preferences.

Winner: Nexgard

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